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Mixture Distributions and the Construction of Reference Ranges for Biochemical parameters

Pakistan Journal of Statistics and Operation Research

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Title Mixture Distributions and the Construction of Reference Ranges for Biochemical parameters
 
Creator Kamal, Shahid
Lawrence, Clive J.
Trewin, Vivian F.
Sekandar, Aisha
 
Description The ability to make use of accurately documented, local and specific, reference ranges is an important part of clinical work. The most readily available, often the only, routinely collected data is that obtained from hospital admissions. A mixture distribution approach is employed to arrive at reference range appropriate to particular groups of patients. A classification rule is used to provide a spectrum of such ranges that allows for the lack of complete separation of the components of the mixture, a common feature when such models are fitted to data. The results of analyses are given for a range of biochemical parameters; in some examples, these are shown separately for males and females, and for those taking, and not taking, a diuretic drug – the most commonly occurring drug-group in the elderly.
 
Publisher College of Statistical and Actuarial Sciences
 
Date 2007-01-01
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://www.pjsor.com/index.php/pjsor/article/view/72
10.18187/pjsor.v3i1.72
 
Source Pakistan Journal of Statistics and Operation Research; Vol 3. No. 1, Jan 2007; 19-30
2220-5810
1816-2711
 
Language eng
 
Relation http://www.pjsor.com/index.php/pjsor/article/view/72/50