Record Details

Test S of Haplotype Concordance and Discordance

Pakistan Journal of Statistics and Operation Research

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Field Value
 
Title Test S of Haplotype Concordance and Discordance
 
Creator Khattak, Mahnaz
Shah, Shuhrat
Din, Salahud
 
Description The test presented here is based upon the proband and his/her affected as well as unaffected siblings. Here, the siblings are analyzed in terms of similarities of haplotypes. The proposed ā€˜Sā€™ test is used in testing hypothesis that a particular disease has random pattern of inheritance against the alternative hypothesis that it has non-random pattern of inheritance. Probability distribution, mean and variance of the test are derived under the null hypothesis of random inheritance of the disease. It is then applied to data set of varying size of sibships having at least one affected and one unaffected sibs to investigate the existence of linkage disequilibrium.
 
Publisher College of Statistical and Actuarial Sciences
 
Date 2007-01-01
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://www.pjsor.com/index.php/pjsor/article/view/76
10.18187/pjsor.v3i1.76
 
Source Pakistan Journal of Statistics and Operation Research; Vol 3. No. 1, Jan 2007; 45-52
2220-5810
1816-2711
 
Language eng
 
Relation http://www.pjsor.com/index.php/pjsor/article/view/76/54